Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1564 | 1564-30616 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, T215F | D67G, K219Q | L100I, K103N | Y181F | T69H, K102Q, D121DH, K122E, D192DH, T200E, E203K, Q207E, D218E, K223Q, L228HR |
| >1564-30616| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKGSHRWRKLVDFRELNKRTQDFWEVQLGIPHP AGIKQNKSVTVLDVGDAYFSVPLHEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIFQYMDDLYVGSHLEIGQHREKIKELREHLLRWGFFTP EQKHQQEPPFRWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V, L90M | L10F, L33F, G73T | L19LI, L63P, I66V, H69R, P79H, I93L, C95F |
| >1564-30616| codons 4-99 TLWQRPFVTIKIGGQIKEALLDTGADDTVFEEMNLPGRWKPKIIGGIGGFVKVRQYDQIP IEVCGRKAITTVLVGHTPVNVIGRNLMTQLGFTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |