Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1560 | 1560-30610 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I47V, I54V, I84V, L90M | L33F, Q58E | L10I, I13V, F53W, D60E, L63P, I66V, H69HY, I72V, G73V, V77L |
| >1560-30610| codons 4-99 TLWQRPIVTVKIGGQLKEALLDTGADDTIFEEMNLPGRWKPKIVGGIGGWVKVREYEQIP IEVCGYKAVVTVLLGPTPVNVIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, M184V, L210W, T215Y | Y188L | T39A, E40F, K43E, V106I, L109V, K122E, V179I, V189I, G196E, I202V, H208Y, R211K, E224D, F227Y, V245E |
| >1560-30610| codons 38-247 CAFLEEEGKISKIGPENPYNTPVFAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSITVVDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIIIYQYVDDLLIGSDLEIEQHRTKVEELRQYLWKWGFYTP DKKHQKDPPYLWMGYELHPDKWTVQPIELP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |