Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1987 | 1987-30602 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L74LV, L210W, T215Y | K219R | Y181YC, Y188L | T39A, K43E, E44D, K102KM, V106VI, L109LI, V118I, K122E, D177E, Q207E, D218E, L228H |
| >1987-30602| codons 38-247 CAELEEDGKISKIGPENPYNTPVFAIKKKNSDKWRKVVDFRELNKRTQDFWEVQLGIPHP AGLKMKKSITVIDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPEIVICQYMDDLLVGSDLEIGQHRTKIEELREHLWRWGFYTP ERKHQKEPPFHWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46IL, I54L, V82A, L90M | L33F, K43T, G73S | L10I, I13IV, K20KR, E35D, M36I, R41K, K55KR, I62V, L63P, A71V, I93L |
| >1987-30602| codons 4-99 TLWQRPIVTVKIGGQLREALLDTGADDTVFEDINLPGKWTPKLIGGIGGFLRVRQYDQVP IEICGHKVISTVLVGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |