Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1985 | 1985-30602 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, L76V, V82A | L10IV, I15V, K20R, M36I, N37D, K55R, L63P, A71V, I72V, I93L |
| >1985-30602| codons 4-99 TLWQRPVVTIKVGGQLREALLDTGADDTILEEIDLPGRWKPKIIGGIGGFIRVRQYDQIP IEICGHKVVGTVVVGPTPANIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70KR, L74I, M184V, T215F | K219Q | K103N | K122E, Q174K, I202V, E203D, Q207E, R211K, V245T |
| >1985-30602| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKNSTRWRKIVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKKNPDIVIYQYVDDLYVGSDLEIGQHRTKVDELREHLLKWGFFTP DQKHQKEPPFLWMGYELHPDKWTVQPITLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |