<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1942 1942-30528 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, L74I, M184V, T215F A62V, V75T, K219E K103N   T39A, T69N, V118I, D123E, I135T, S162D, D177E, V179I, T200TA, F214L, L228H, V245M  
>1942-30528| codons 38-247
CAELEKEGKISKIGPENPYNTPVFVIKKKNSNRWRKITDFRELNKRTQDFWEVQLGIPHP
AGLKKNKSVTVLDVGDAYFSIPLDKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQDSMTKILEPFRKQNPEIIIYQYVDDLYVGSDLEIGQHRAKIEELRQHLLRWGLFTP
DEKHQKEPPFHWMGYELHPDKWTVQPIMLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82A, L90M F53L, Q58E, G73S L10I, I15V, N37D, K55R, I62V, L63P, A71V, I72L, I85V  
>1942-30528| codons 4-99
TLWQRPIVTIKVGGQLKEALLDTGADDTVLEEMDLPGRWKPKIIGGIGGLVRVREYDQVP
IEICGHKVLSTVLVGPTPANIVGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006