Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1940 | 1940-30521 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, I84V, L90M | L33F, T74P | L10I, V11L, I13V, R41K, K55KR, D60E, L63P, A71V, V77VI, I93L |
| >1940-30521| codons 4-99 TLWQRPILTVKIGGQLKEALLDTGADDTVFEEMNLPGKWKPKLIGGIGGFVRVRQYEQIP IEICGHKVIGPVLIGPTPVNVIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70G, L74V, M184V | Y181C, G190A | K49R, S68G, S105T, V111VIM, D123E, I135T, V245Q |
| >1940-30521| codons 38-247 CTEMEKEGKISRIGPENPYNTPVFAIKKKNGTGWRKVVDFRELNKRTQDFWEVQLGIPHP AGLKKKKTVTVLDMGDAYFSVPLDKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVICQYVDDLYVASDLEIGQHRTKIEELRQHLLRWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |