Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1798 | 1798-30611 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, L74I, T215F | V75L, K219Q | L100I, K103N | V108VI | L109LM, D123E, S162Y, Q174H, D177E, I202V, Q207D, R211K, V241I |
| >1798-30611| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKNSTRWRKILDFRELNKRTQDFWEVQLGIPHP AGIKKNKSVTIMDVGDAYFSVPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQYSMTKILEPFRKHNPEIVIYQYMDDLYVGSDLEIGQHRTKVEELRDHLLKWGFFTP DQKHQKEPPFLWMGYELHPDKWTIQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I47V, I54M, I84V | L33F, F53FL, G73S | L10V, I13V, K55KN, D60DE, L63P, V77I, Q92K |
| >1798-30611| codons 4-99 TLWQRPVVTVKIGGQLKEALLDTGADDTVFEEMNLPGRWKPKIVGGIGGLMNVRQYEQIP IEICGHKAISTVLIGPTPVNVIGRNLLTKIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |