Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1797 | 1797-30530 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67DN, L74I, V75MT, M184V, L210W, T215Y | F77FL, K219N | K103N | V108I | T39A, S68G, K101Q, V118VI, K122E, I142V, S162SAGT, I178M, T200A, E203K, Q207E, R211K, F227FY | K64KE |
| >1797-30530| codons 38-247 CAELEKEGKISKIGPENPYNTPVFAIEKKNGTKWRKITDLRELNKRTQDFWEVQLGIPHP AGLQKNKSVTILDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP AIFQTSMTKILEPFRKQNPDMVIYQYVDDLYVGSDLEIGQHRAKIKELREHLWKWGFYTP DNKHQKEPPYLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, I84V, L90M | L10FI, G73S | I15V, K20R, E35D, M36I, N37T, R57K, I62V, L63P, A71V, I93L |
| >1797-30530| codons 4-99 TLWQRPIVTIKVGGQLREALLDTGADDTVLEDITLPGRWKPKMIGGIGGFVKVKQYDQVP IEICGHKVISTVLVGPTPVNVIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |