<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1797 1797-30530 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, I84V, L90M L10FI, G73S I15V, K20R, E35D, M36I, N37T, R57K, I62V, L63P, A71V, I93L  
>1797-30530| codons 4-99
TLWQRPIVTIKVGGQLREALLDTGADDTVLEDITLPGRWKPKMIGGIGGFVKVKQYDQVP
IEICGHKVISTVLVGPTPVNVIGRNLMTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67DN, L74I, M184V, L210W, T215Y V75MT, F77FL, K219N K103N V108I T39A, S68G, K101Q, V118VI, K122E, I142V, S162SAGT, I178M, T200A, E203K, Q207E, R211K, F227FY K64KE
>1797-30530| codons 38-247
CAELEKEGKISKIGPENPYNTPVFAIEKKNGTKWRKITDLRELNKRTQDFWEVQLGIPHP
AGLQKNKSVTILDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP
AIFQTSMTKILEPFRKQNPDMVIYQYVDDLYVGSDLEIGQHRAKIKELREHLWKWGFYTP
DNKHQKEPPYLWMGYELHPDKWTVQPIVLP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006