<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1210 1210-30508 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, Y115F, Q151M A62V, K70KT, V75I, F77L, F116Y K101KE, Y188L, G190A   S68G, V106VI, V118I, D121HY, K122E, S162C, R172K, D177E, T200A, V245T  
>1210-30508| codons 38-247
CTEMEKEGKISKIGPENPYNTPVFVIKRKDGTTWRKLIDLRELNKRTQDFWEVQLGIPHP
AGLEKKKSITVLDVGDAFYSIPLYEDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSP
AIFQCSMTKILEPFKKQNPEIVIYQYMDDLLVASDLEIGQHRAKIEELRQHLLRWGFTTP
DKKHQKEPPFLWMGYELHPDKWTVQPITLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A, L90M V11I L10I, T12A, I15V, L19T, K20I, E34Q, L63P, A71I, I93L  
>1210-30508| codons 4-99
TLWQRPIIAIKVGGQTIEALLDTGADDTVLQEMNLPGRWKPKMIGGIGGFVKVRQYDQIP
IEICGHKIIGTVLVGPTPANIIGRNLMTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006