Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1960 | 1960-30714 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L90M | Q58E | L10V, I13V, K14R, I15V, Q18E, K20V, I62V, L63P, A71V, V77I, Q92K |
| >1960-30714| codons 4-99 TLWQRPVVTVRVGGELVEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVREYDQVP IEICGHKVIGTVLIGPTPVNIIGRNLMTKIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67DN, V75VM, L210LW, T215TNSY | K219N | K103N | V108VI, F227FL | T107S, L109LIM, D121H, K122E, I135T, S162C, Q174QR, D177DE, I178IL, G196GE, I202IV, H208HY, R211K | L228LFHY |
| >1960-30714| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKNSTKWRKLMDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVSIMDVGDAYFSVPLHEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFRKRNPELVIYQYMDDLYVGSDLEIEQHRTKVEELRQYLWKWGFYTP DNKHQKEPPLYWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |