<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1201 1201-30307 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
D30N, I54V, V82A, L90M L10F, L33F, Q58E, N88D I13V, K20R, E35D, M36I, N37S, R41K, L63P, A71T  
>1201-30307| codons 4-99
TLWQRPFVTVKIGGQLREALLDTGADNTVFEDISLPGKWKPKMIGGIGGFVKVREYDQIP
IEICGHKTIGTVLVGPTPANIIGRDLMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67DN, V75AT, M184V, L210W, T215Y A62V K103N   K43E, V118I, D123E, I142V, T200A, R211K, L228LH, V245Q  
>1201-30307| codons 38-247
CTELEEEGKISKIGPENPYNTPVFVIKKKNSTKWRKLTDFRELNKRTQDFWEVQLGIPHP
AGLKKNKSVTVLDVGDAYFSIPLDKEFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRAKIEELRQHLWKWGFYTP
DKKHQKEPPFHWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006