Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1885 | 1885-30611 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69D, Y115F, Q151M, M184MV | V75I, F77L, F116Y, K219Q | Y181C, G190A | K101Q, K122E, D123N, Q174R, E203Q, R206RK, Q207E, F214FL |
| >1885-30611| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKNSDKWRKLIDLRELNKRTQDFWEVQLGIPHP AGLQKKKSVTVLDVGDAFYSVPLDENFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSP AIFQSSMTKILEPFRKRNPDIVICQYVDDLYVASDLEIGQHRTKIQELKEHLLRWGLTTP DQKHQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I47V, I54M, I84V, L90M | L10F, V11I, L33F, Q58E, L89V | I13V, I15V, K20IV, E35DN, M36I, L63P, A71V |
| >1885-30611| codons 4-99 TLWQRPFITVKVGGQLVEALLDTGADDTIFENINLPGRWKPKIVGGIGGFMKVREYDQIP IEICGHKVIGTVLVGPTPVNVIGRNVMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |