Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1834 | 1834-30522 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32VI, I47V, I54IL, L90M | L10F, I84IM | I13V, I15V, K20I, E35D, M36I, R41RK, L63P, T74S |
| >1834-30522| codons 4-99 TLWQRPFVTVKVGGQLIEALLDTGADDTILEDINLPGKWKPKMVGGIGGFLKVRQYDQIP IEICGHKAIGSVLVGPTPVNMIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T215Y | D67DH, K219N | K101H | T39A, K43E, V60I, T69N, K122E, D123E, I135T, I142V, Q174K, I178IFL, G196GE, Q207S | N57NH, S68DN, S162*CWY |
| >1834-30522| codons 38-247 CAELEEEGKISKIGPENPYHTPIFAIKKKHNNKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLHKKKSVTVLDVGDAYFSVPLDEEFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSP AIFQYSMTKILEPFRKKNPDLVIYQYMDDLYVGSDLEIEQHRTKIEELRSHLLRWGFYTP DNKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |