<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1688 1688-30417 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, M184V, L210W, T215Y V75M, K219E K103N, Y181YC, G190GA V108VI T39A, V60I, R83K, A98S, K122E, I135L, T139TM, S162A, R211K, H221HY, L228H  
>1688-30417| codons 38-247
CAELEKEGKISKIGPENPYNTPIFAIKKKNSTRWRKLMDFRELNKKTQDFWEVQLGIPHP
SGLKKNKSVTILDVGDAYFSVPLDEDFRKYTAFTIPSLNNEMPGIRYQYNVLPQGWKGSP
AIFQASMTKILEPFRKQNPDIVICQYVDDLYVASDLEIGQHRTKIEELRQHLWKWGFYTP
DEKYQKEPPFHWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI, I54V, V82VA, L90M G73S L10V, I15V, K20M, E35G, M36I, N37ND, I62V, L63P, C67F, I72L  
>1688-30417| codons 4-99
TLWQRPVVTIKVGGQLMEALLDTGADDTVLEGIDLPGRWKPKIIGGIGGFVKVRQYDQVP
IEIFGHKALSTVLVGPTPANIIGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006