Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1159 | CA7500 | U.S. | 1997 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 9 |
| 2 | DDI | 26 |
| 3 | D4T | 18 |
| 4 | AZT+D4T+IDV | 26 |
| 5 | AZT+DDI+NVP+RTV+SQV | 13 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, V82A, I84V | L10FY | I15V, D60E, L63P, K70T, L89M |
| >CA7500| codons 1-99 PQITLWQRPFVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYE QIPIEICGHTAIGTVLVGPTPANVIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V106A | V35L, V179I, G196E, T200A, E203K, Q207E, E248D, A272P, T286A, E297K | C280CR |
| >CA7499| codons 1-298 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALLEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSATVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII YQYMDDLYVGSDLEIEQHRAKIKELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLRKLLRGAKALTEVIPLTKE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |