Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1633 | 1633-30313 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151M | A62V, K70N, V75I, F116Y | Y181C | A98G | S68G, V118I, K122DN, D123E, T139TA, R172K, V179I, G196E, F214L, L228R, V245E |
| >1633-30313| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFVIKKKDGTNWRKLIDFRELNKRTQDFWEVQLGIPHP GGLKKKKSVTVLDVGDAYYSIPLDNEFRKYTAFTIPSINNEAPGIRYQYNVLPMGWKGSP AIFQSSMTKILEPFKKQNPDIIICQYMDDLYVGSDLEIEQHRTKIEELRQHLLRWGLTTP DKKHQKEPPFRWMGYELHPDKWTVQPIELP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, G48V, I54S, V82C, L90M | L33LF | L10I, R41K, L63GS, A71V, V77I, I93L |
| >1633-30313| codons 4-99 TLWQRPIVTIKIGGQLKEALLDTGADDTVFEEMNLPGKWKPKIIVGIGGFSKVRQYDQIS IEICGHKVIGTVLIGPTPCNIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |