Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1638 | 1638-30311 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74I, M184V, L210W | K103N | P225H | K102Q, K122E, S162C, G196E, T200A, Q207E, R211K |
| >1638-30311| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKIVDFRELNKRTQDFWEVQLGIPHP AGLKQNKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIEQHRAKIEELREHLWKWGFTTP DKKHQKEHPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32VI, M46MI, I47IV, I54IM, V82A | L24LI, L33LF | L10I, R41K, Q61QHKN, I62IV, L63AT, I64V, E65D, T74S, V77I, I85IV |
| >1638-30311| codons 4-99 TLWQRPIVTIKIGGQLKEALIDTGADDTIFEEMNLPGKWKPKIVGGIGGFMKVRQYDNVT VDICGHKAIGSVLIGPTPANIVGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |