Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1631 | 1631-30304 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, M184V, L210W, T215Y | K219E | K101E, Y181C, G190A | T39A, V60I, S105T, K122E, S162A, Q174H, G196E, E203D, R211RQ, D218E, H221Y, L228R |
| >1631-30304| codons 38-247 CAELEKEGKISKIGPENPYNTPIFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLEKKKTVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQASMTKILEPFRKHNPDIVICQYVDDLYVASDLEIEQHRTKIDELRQHLWQWGFYTP EEKYQKEPPFRWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54A, V82A, L90M | V11I, L33F | L10I, T12P, I13V, K14R, E34Q, L63P, A71V, I72V, V77I, Q92K, I93L |
| >1631-30304| codons 4-99 TLWQRPIIPVRIGGQLKEALLDTGADDTVFQEMNLPGRWKPKMIGGIGGFAKVRQYDQIP IEICGHKVVGTVLIGPTPANIIGRNLMTKLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |