<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1179 1179-30609 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V, V82A L24I, K43T L10I, T12P, I15V, L19I, E35ED, M36MI, R41K, K55R, D60E, I62V, L63P, A71V, I72IT, I93L  
>1179-30609| codons 4-99
TLWQRPIVPIKVGGQIKEALIDTGADDTVLEDINLPGKWTPKIIGGIGGFVRVRQYEQVP
IEICGHKVTGTVVVGPTPANIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T69DEKN, K70EG, Y115F, Q151M, M184V A62V, D67DG, V75T K101E, Y181C, G190A E138K K43E, K49R, S68SG, K82KR, D123E, I135T, D177E, Q207N, R211K, F214L, L228LH, V245E  
>1179-30609| codons 38-247
CTEMEEEGKISRIGPENPYNTPVFVIKKKGGNGWRKLTDFRELNRRTQDFWEVQLGIPHP
AGLEKKKSVTVLDVGDAFFSVPLDKEFRKYTAFTIPSTNNKTPGIRYQYNVLPMGWKGSP
AIFQSSMTKILEPFRKQNPEIVICQYVDDLYVASDLEIGQHRTKIEELRNHLLKWGLTTP
DKKHQKEPPFHWMGYELHPDKWTVQPIELP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006