<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1170 1170-30305 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, M184V, L210W, T215Y   K103N, M230L V108I E44D, S68G, K122P, I135V, K166R, D177E, T200TA, R211K, V245A  
>1170-30305| codons 38-247
CTELEKDGKISKIGPENPYNTPVFAIKKKDGTKWRKVVDFRELNKRTQDFWEVQLGIPHP
AGLKKNKSVTILDVGDAYFSVPLDPDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP
AIFQSSMTRILEPFRKQNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELRQHLWKWGFYTP
DKKHQKEPPFLWLGYELHPDKWTVQPIALP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A, L90M L23I, K43T, F53L, N88D L10I, K20R, E35D, M36I, R57K, I62V, L63P, A71V  
>1170-30305| codons 4-99
TLWQRPIVTIKIGGQLREAILDTGADDTVLEDINLPGRWTPKMIGGIGGLVKVKQYDQVP
IEICGHKVIGTVLVGPTPANIIGRDLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006