Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1906 | 1906-30616 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, M184V, L210W, T215Y | K219R | K103N | A98G | K43Q, E44D, V118I, K122E, S162C, Q174QR, D177E, I178IM, V179VI, G196E, E203K, Q207E, R211K, K223E, L228H, Q242H |
| >1906-30616| codons 38-247 CTELEQDGKISKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHP GGLKKNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFRKRNPEMIIYQYVDDLYVGSDLEIEQHRTKIKELREHLWKWGFYTP DRKHQEEPPFHWMGYELHPDKWTVHPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, I47V, I54V, V82A, L90M | L33F, K43T, F53L | L10IV, I13IV, K20R, E35D, M36I, D60E, I62V, L63P, A71V, I93L |
| >1906-30616| codons 4-99 TLWQRPVVTVKIGGQLREALLDTGADDTVFEDINLPGRWTPKIVGGIGGLVKVRQYEQVP IEICGHKVIGTVLVGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |