Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1164 | 1164-30311 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48GA, I54V, V82A | L24I, L33F, K43T | L10I, T12P, I15IV, L19T, K20T, M36L, L63P, A71V, Q92K | T91TAGS |
| >1164-30311| codons 4-99 TLWQRPIVPIKVGGQTTEALIDTGADDTVFEELNLPGRWTPKMIAGIGGFVKVRQYDQIP IEICGHKVIGTVLVGPTPANIIGRNLLSKIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69D, K70R, Q151M, M184V | F116Y, T215V, K219Q | K101E, Y181C | K49E, V118I, K122E, I135T, F214L, L228H |
| >1164-30311| codons 38-247 CTEMEKEGKISEIGPENPYNTPVFAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLEKKKSVTVLDVGDAYYSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSP AIFQSSMTKILEPFRKQNPDIVICQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGLVTP DQKHQKEPPFHWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |