Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1162 | 1162-30605 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215Y | E138K | S68G, V90I, A98S, K101Q, D123E, I142T, I195IL, G196E, I202V, L210LF, R211KQ |
| >1162-30605| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKDGTKWRKLVDFRELNKRTQDFWEIQLGIPHP SGLQKKKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSINNKTPGTRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLELEQHRTKVEELRQHLFQWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I50V, I54V, V82A | L33F, K43T, N83ND | L10I, K20R, E35D, M36IL, R57K, I62V, L63P, I72V, L89LM |
| >1162-30605| codons 4-99 TLWQRPIVTIKIGGQLREALLDTGADDTVFEDLNLPGRWTPKMIVGVGGFVKVKQYDQVP IEICGHKAVGTVLVGPTPADIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |