<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1161 1161-30529 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, L74LV, Y115YF, Q151M A62V, K70T, V75I, F116Y K103S, G190A   V60I, S68G, T69I, R83K, V118I, K122P, D123E, I135IT, T139I, R172K, Q174R, D177E, I178IM, D192DN, Q197E, E204K, Q207E, R211K, F214L  
>1161-30529| codons 38-247
CTEMEKEGKISKIGPENPYNTPIFVIKRKDGITWRKVIDFRELNKKTQDFWEVQLGIPHP
AGLKKSKSVTVLDVGDAFYSIPLDPEFRKYTAFTIPSTNNEIPGIRYQYNVLPMGWKGSP
AIFQSSMTKILEPFKKRNPEMVIYQYMDDLYVASNLEIGEHRTKIEKLREHLLKWGLTTP
DKKHQKEPPFLWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47A, L90M L23LI, F53FL L10V, K20R, E35D, M36I, N37E, L63P, A71LV, V77I, I93L  
>1161-30529| codons 4-99
TLWQRPVVTIKIGGQLREAILDTGADDTILEDIELPGRWKPKIAGGIGGLIKVRQYDQIP
IEICGHKVIGTVLIGPTPVNIIGRNLMTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006