Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2061 | 2061-30707 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T215FL | K219E | Y181C | T69N, V90I, K122P, S162G, K173E, T200TA, I202IV, R211K |
| >2061-30707| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKNSNKWRKLVDFRELNKRTQDFWEIQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDPDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQGSMTKILEPFREQNPDIVICQYMDDLYVGSDLEIGQHRAKVEELRQHLLKWGFLTP DEKHQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I84V, L90M | G73GC | L10LI, T12K, L19LI, N37D, I62V, L63P, H69HR, I72IM, V77I |
| >2061-30707| codons 4-99 TLWQRPIVKIKIGGQIKEALLDTGADDTVLEEMDLPGRWKPKIIGGIGGFIKVRQYDQVP IEICGRKAMCTVLIGPTPVNVIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |