Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2042 | 2042-30604 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69DN, L74V, M184V, L210W, T215Y | K219Q | K101P, K103S | T39A, K43E, V118I, K122E, I142IT, Q174R, D177DE, I178M, V179I, D192N, G196E, E203K, Q207E, R211K, K223E, L228H |
| >2042-30604| codons 38-247 CAELEEEGKISKIGPENPYNTPVFAIKKKNSNKWRKVVDFRELNKRTQDFWEVQLGIPHP AGLPKSKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGTRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKRNPEMIIYQYVDDLYVGSNLEIEQHRTKIKELREHLWKWGFYTP DQKHQEEPPFHWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54L, V82A, L90M | L10F, L33F, K43T, G73A | I13V, G16GA, K20R, E35D, M36I, R57RK, I62V, L63P, A71V, I93L |
| >2042-30604| codons 4-99 TLWQRPFVTVKIAGQLREALLDTGADDTVFEDINLPGRWTPKMIGGIGGFLKVKQYDQVP IEICGHKVIATVLVGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |