<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1948 1948-30528 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184V, L210W, T215Y V75S, K219Q K101P, G190A   T39N, K64H, V118I, K122E, I135T, D177E, V179I, I180V, T200A, H208Y, R211K, D218E, L228H  
>1948-30528| codons 38-247
CNELEKEGKISKIGPENPYNTPVFAIHKKNSTKWRKVSDFRELNKRTQDFWEVQLGIPHP
AGLPKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPEIIVYQYVDDLYVASDLEIGQHRAKIEELRQYLWKWGFYTP
EQKHQKEPPFHWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48V, I54AV, V82A, I84V, L90M L33F, Q58E, G73GS L10I, T12P, I13IV, L19T, D60E, I62V, L63P, I66IV, A71T, V75VI, V77I, T91S, I93L, C95F  
>1948-30528| codons 4-99
TLWQRPIVPVKIGGQTKEALLDTGADDTVFEEMNLPGRWKPKMIVGIGGFVKVREYEQVP
IEVCGHKTISTILIGPTPANVIGRNLMSQLGFTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006