Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1918 | 1918-30520 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I50V, I54V, V82A, L90M | L33F, T74P | L10V, I13V, G16A, K55R, Q61E, L63P, A71V, I72V, V77I, I93L |
| >1918-30520| codons 4-99 TLWQRPVVTVKIAGQLKEALLDTGADDTVFEEMNLPGRWKPKIIGGVGGFVRVRQYDEIP IEICGHKVVGPVLIGPTPANIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, M184V, L210W, T215F | G190A | K101A, K102Q, V118I, I142V, S162C, I178F, T200TA, R211K |
| >1918-30520| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHP AGLAQKKSVTVLDVGDAYFSIPLDKDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP AIFQCSMTKILEPFRKQNPDFVIYQYVDDLYVASDLEIGQHRAKIEELRQHLWKWGFFTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |