Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2202 | 2202-30717 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, M184V, L210W, T215Y | K219KR | G190A | K101H, V108I | K43Q, E44D, V60I, V106VI, V118I, D123E, V189VI, T200A, E203D, H208Y, R211K, H221Y, V245M |
| >2202-30717| codons 38-247 CTELEQDGKISKIGPENPYNTPIFAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLHKKKSITILDVGDAYFSIPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYVDDLYIASDLEIGQHRAKIDELRQYLWKWGFYTP DRKYQKEPPFLWMGYELHPDKWTVQPIMLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V, L90M | L10F, T74P | I13V, L33M, K55R, R57K, I62V, L63P, C67CY, L89I, T91S |
| >2202-30717| codons 4-99 TLWQRPFVTVKIGGQLKEALLDTGADDTVMEEMNLPGRWKPKIIGGIGGFVRVKQYDQVP IEIYGHKAIGPVLVGPTPVNVIGRNIMSQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |