Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1151 | 1151-30514 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A, I84V | L10F, V11VI, L24I, L33F, L89LV | I13V, K55R, R57K, D60DE, L63P, A71L, I72IT, I93L | T91TCS |
| >1151-30514| codons 4-99 TLWQRPFITVKIGGQLKEALIDTGADDTVFEEMNLPGRWKPKLIGGIGGFVRVKQYEQIP IEICGHKLTGTVLVGPTPANVIGRNVLSQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74LV, V75VIM, M184V, L210W, T215Y | F77FL, K219KR | L100LI, K103KN | A98G, V108VI | T39K, K43E, E44D, R83K, V118I, K122E, D123E, D177G, V179I, G196E, E203K, Q207E, H208Y, R211K, K223T, L228R |
| >1151-30514| codons 38-247 CKELEEDGKISKIGPENPYNTPVFAIKKKDSTKWRKVMDLRELNKKTQDFWEVQLGIPHP GGIKKNKSVTILDVGDAYFSIPLDEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPGIIIYQYVDDLYVGSDLEIEQHRTKIKELREYLWKWGFYTP DRKHQTEPPFRWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |