<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
LR-JART JARTW24 Spain 1996 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 NRTI NA
2 NRTI+IDV 24

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    K20R, E35D, M36I, R57K, L63P G51V, K70Y
>JARTW24| codons 1-99
PQITLWQRPLVTIKIGGQLREALLDTGADDTVLEDINLPGRWKPKMIGGIVGFIKVKQYD
QIPIEICGHYAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Ruiz, L Efficacy of adding indinavir to previous reverse transcriptase nucleoside analogues in relation to genotypic and phenotypic resistance development in advanced HIV-1-infected patients. JAIDS, 1998
Wu, TD Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments. J Virol, 2003
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005