Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1860 | 1860-30520 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A, I84V | L24I, L33F | L10I, L19LI, E35D, N37S, I62V, L63P, A71V, T91S |
| >1860-30520| codons 4-99 TLWQRPIVTIKIGGQIKEALIDTGADDTVFEDMSLPGRWKPKIIGGIGGFVKVRQYDQVP IEICGHKVIGTVLVGPTPANVIGRNLLSQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | K219KR | K43Q, V60I, K122E, I135V, Q145M, K166R, T200E, E203K, Q207E, R211K |
| >1860-30520| codons 38-247 CTELEQEGKISKIGPENPYNTPIFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSVNNETPGIRYMYNVLPQGWKGSP AIFQSSMTRILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHREKIKELREHLWKWGFYTP DRKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |