<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1472 1472-30424 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, V75M, M184V, L210W, T215Y K219R Y188L A98G K43N, E44D, V60I, K102Q, V106I, V118I, K122E, I142V, G196E, E203V, H208Y, R211K, K223E, L228H, V245E W71WR
>1472-30424| codons 38-247
CTELENDGKISKIGPENPYNTPIFAIKKKNSTKRRKLMDFRELNKRTQDFWEVQLGIPHP
GGLKQKKSITVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPDIVIYQYVDDLLVGSDLEIEQHRTKIVELRQYLWKWGFYTP
DRKHQEEPPFHWMGYELHPDKWTVQPIELP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47V, I84V, L90M L10F, L33IM, N88D I13V, E35D, M36I, K55R, R57K, I62V, L63P, I66V, A71V, I72L, V77T, I93L, C95F, F99Y  
>1472-30424| codons 4-99
TLWQRPFVTVKIGGQLKEALLDTGADDTIMEDINLPGRWKPKIVGGIGGFIRVKQYDQVP
IEVCGHKVLGTVLTGPTPVNVIGRDLMTQLGFTLNY

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006