<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1469 1469-30422 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54IV, V82A, L90M V11IL, L33F, F53L L10I, I15V, K20V, L24F, E35N, M36I, R41K, K45KR, K55KR, D60E, I62V, L63P, A71I, I85IV, L89LIM  
>1469-30422| codons 4-99
TLWQRPILTIKVGGQLVEALFDTGADDTVFENINLPGKWKPRMIGGIGGLVRVRQYEQVP
IEICGHKIIGTVLVGPTPANIVGRNMMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70KR, M184V, L210W, T215Y V75M, K219Q K103N A98G T39K, K43E, V60I, V111I, V118VI, K122E, I135IL, D177DE, T200TA, E203K, Q207E, H208Y, R211K, K223Q, L228H Q145QK
>1469-30422| codons 38-247
CKELEEEGKISKIGPENPYNTPIFAIKKKNSTRWRKLMDFRELNKRTQDFWEVQLGIPHP
GGLKKNKSVTVLDIGDAYFSIPLDEDFRKYTAFTIPSLNNETPGIRYKYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPEIVIYQYVDDLYVGSDLEIGQHRAKIKELREYLWKWGFYTP
DQKHQQEPPFHWMGYELHPDKWTVQPIVLP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006