Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1286 | 1286-30404 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T69D, K70R | K103N | P225H | W88C, I142V, I178M, F214L, L228R, V245E |
| >1286-30404| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKDSDRWRKLVDFRELNKRTQDFCEVQLGIPHP AGLKKNKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDMVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTP DKKHQKEHPFRWMGYELHPDKWTVQPIELP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I84V | L24I | L10I, I13V, K14KR, L19V, K20R, E35D, M36I, L63P, A71T |
| >1286-30404| codons 4-99 TLWQRPIVTVRIGGQVREALIDTGADDTVLEDINLPGRWKPKLIGGIGGFIKVRQYDQIP IEICGHKTIGTVLVGPTPVNVIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |