Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1464 | 1464-30603 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210W, T215CY | A62V | L100I, K103N | K43E, E44A, V118I, K122E, T139R, D177E, I202V, Q207E, L228R | E53EK |
| >1464-30603| codons 38-247 CTELEEAGKISKIGPKNPYNTPVFVIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGIKKNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNERPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPEIVIYQYVDDLYVGSDLEIGQHRTKVEELREHLWRWGFYTP DKKHQKEPPFRWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I47IV, I54M, I84V, L90M | L10F, L33LF | E34EQ, I62IV, L63P, I66V, A71V, V77I, I85IV, I93L | D29DV |
| >1464-30603| codons 4-99 TLWQRPFVTIKIGGQLKEALLDTGAVDTVFQEMNLPGRWKPKIVGGIGGFMKVRQYDQVP IEVCGHKVIGTVLIGPTPVNVVGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |