<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1465 1465-30604 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I50V, I54V, V82A, L90M V11I, L33F, Q58E L10IV, I13V, K20R, E35D, M36I, N37E, P39PS, K55R, R57RK, D60E, I62V, L63P, A71V  
>1465-30604| codons 4-99
TLWQRPVITVKIGGQLREALLDTGADDTVFEDIELSGRWKPKIIGGVGGFVRVKEYEQVP
IEICGHKVIGTVLVGPTPANIIGRNLMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, L74I, M184V, L210W, T215F   Y181C A98G, V108I K43N, V118I, K122E, F171Y, V179I, V189VI, Q197E, E203D, Q207E, R211RK, D218DE, K219G, L228H P170PHQ
>1465-30604| codons 38-247
CTELENEGKISKIGPENPYNTPVFAIKKKNSDKWRKIVDFRELNKRTQDFWEVQLGIPHP
GGLKKKKSVTILDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEQYRKQNPDIIICQYVDDLYIGSDLEIGEHRTKIDELREHLWKWGFFTP
EGKHQKEPPFHWMGYELHPDKWTVQPIVLP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006