Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1793 | 1793-30609 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70KR, L74I, M184V, T215F | K219Q | Y181V | K101Q, S162SC, E169D, Q174N, R211S, L228H |
| >1793-30609| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKNSTRWRKIVDFRELNKRTQDFWEVQLGIPHP AGLQKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILDPFRKNNPDIVIVQYVDDLYVGSDLEIGQHRTKIEELRQHLLSWGFFTP DQKHQKEPPFHWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54M, L76V, V82A, L90M | L10IV, I15V, E34Q, M36I, R41K, K55R, I62V, L63P, A71V, I72IV, T74S, I93L |
| >1793-30609| codons 4-99 TLWQRPVVTIKVGGQLKEALLDTGADDTVLQEINLPGKWKPKIIGGIGGFMRVRQYDQVP IEICGHKVVGSVVVGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |