<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1792 1792-30529 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, I84V, L90M G73T L10I, K20I, R41K, Q61H, L63P, I64IV, I66IV, A71V, I72V, V77I  
>1792-30529| codons 4-99
TLWQRPIVTIKIGGQLIEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFVKVRQYDHIP
VEVCGHKVVTTVLIGPTPVNVIGRNLMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69D, K70R, Y115YF, Q151M, M184V, T215F A62AV, V75VI, F77FL, K219EQ Y181C, G190GS A98G, V108I K49KR, V106VI, K122E, I135IT, T139TA, K173N, Q174K, D177E, V189VI, T200A, I202V, Q207E, R211K, F214L, H221HY, L228H  
>1792-30529| codons 38-247
CTEMEKEGKISRIGPENPYNTPVFVIKKKNSDRWRKLIDLRELNKRTQDFWEVQLGIPHP
GGLKKKKSITILDVGDAFFSVPLDEDFRKYTAFTIPSTNNEAPGIRYQYNVLPMGWKGSP
AIFQSSMTKILEPFRNKNPEIVICQYVDDLYISSDLEIGQHRAKVEELREHLLKWGLFTP
DQKYQKEPPFHWMGYELHPDKWTVQPIVLP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006