Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1791 | 1791-30528 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L76V, I84V, L90M | L10F | N37D, L63P, A71V, I72R, I93L |
| >1791-30528| codons 4-99 TLWQRPFVTIKIGGQLKEALLDTGADDTVLEEMDLPGRWKPKIIGGIGGFIKVRQYDQIP IEICGHKVRGTVVVGPTPVNVIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R | K103N | K46Q, S68G, A98S, V118I, D121Y, K122E, E169D, G196E, T200A, Q207H, R211K, F214L | E194T |
| >1791-30528| codons 38-247 CTEMEKEGQISKIGPENPYNTPVFAIKRKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHP SGLKKNKSVTVLDVGDAYFSIPLYEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILDPFRKQNPDIVIYQYMDDLYVGSDLTIEQHRAKIEELRHHLLKWGLTTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |