<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1719 1719-30512 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, V75M, M184MV, L210W, T215Y K219N L100I, K103N   T39A, V60I, A98AS, V118I, K122E, I135T, A158AS, G196D, T200A, E203K, H208Y, R211K, K223Q, L228H E44DY
>1719-30512| codons 38-247
CAELEKYGKISKIGPENPYNTPIFAIKKKNSDKWRKLMDFRELNKRTQDFWEVQLGIPHP
SGIKKNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
SIFQSSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIDQHRAKIKELRQYLWKWGFYTP
DNKHQQEPPFHWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V82VA K43KT, L89LV L10LI, I13IV, K20KM, M36I, I62V, L63P  
>1719-30512| codons 4-99
TLWQRPIVTVKIGGQLMEALLDTGADDTVLEEINLPGRWTPKMIGGIGGFIKVRQYDQVP
IEICGHKAIGTVLVGPTPANIIGRNVLTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006