Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1717 | 1717-30424 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I54V, V82A, L90M | L10IV, I13IV, K14KR, K20R, M36I, N37ND, L63P, A71V, I72V, I93M |
| >1717-30424| codons 4-99 TLWQRPVVTVRIGGQLREALLDTGADDTILEEIDLPGRWKPKIIGGIGGFVKVRQYDQIP IEICGHKVVGTVLVGPTPANIIGRNLMTQMGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69TADN, L74V, L210W, T215Y | D67G, K219R | L100I, K103N | P225H, K238T | K43Q, E44D, V118VI, K122E, I135T, E138Q, S162C, R172RK, T200TA, I202V, Q207QE, R211K |
| >1717-30424| codons 38-247 CTELEQDGKISKIGPENPYNTPVFAIKKKGSNKWRKVVDFRELNKRTQDFWEVQLGIPHP AGIKKNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNQTPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFKKQNPDIVIYQYMDDLYVGSDLEIGQHRAKVEELREHLWKWGFYTP DRKHQKEHPFLWMGYELHPDTWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |