<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1440 1440-30527 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, K65R, K70R, Q151M, T215F V75I, F116Y, K219E K103S, Y181C, G190A V108I S68G, T69TI, L109I, V118I, D123E, I135T, T139I, T165I, Q174H, D177E, I202V, F214L, L228H, I244V, V245M  
>1440-30527| codons 38-247
CTELEKEGKISKIGPENPYNTPVFAIKRKDGIRWRKLIDFRELNKRTQDFWEVQLGIPHP
AGLKKSKSVTIIDVGDAYYSIPLDKEFRKYTAFTIPSTNNEIPGIRYQYNVLPMGWKGSP
AIFQSSMIKILEPFRKHNPEIVICQYMDDLYVASDLEIGQHRTKVEELRQHLLRWGLFTP
DEKHQKEPPFHWMGYELHPDKWTVQPVMLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I54V, V82A, L90M L33F, F53L, L89V L10I, I13V, L19T, K20R, E35D, M36I, N37DE, L63P, I66F, A71V, I93V  
>1440-30527| codons 4-99
TLWQRPIVTVKIGGQTREALLDTGADDTIFEDIELPGRWKPKIIGGIGGLVKVRQYDQIP
IEFCGHKVIGTVLVGPTPANIIGRNVMTQVGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006