<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1441 1441-30527 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184MV, L210W, T215Y K219R Y181C, G190A V108I T39S, E44D, V90VI, K101Q, K102Q, K103R, V118I, K122E, I135T, I142V, S162Y, T200E, E203D, H208Y, R211N, H221Y  
>1441-30527| codons 38-247
CSELEKDGKISKIGPENPYNTPVFAIKKKNSTKWRKVVDFRELNKRTQDFWEIQLGIPHP
AGLQQRKSVTILDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSP
AIFQYSMTKILEPFRKQNPDIVICQYVDDLYVASDLEIGQHREKIDELRQYLWNWGFYTP
DRKYQKEPPFLWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A L10F, L24I, L33F, Q58E E35D, M36I, N37DE, D60E, I62V, L63P, L89M  
>1441-30527| codons 4-99
TLWQRPFVTIKIGGQLKEALIDTGADDTVFEDIELPGRWKPKLIGGIGGFVKVREYEQVP
IEICGHKAIGTVLVGPTPANIIGRNMLTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006