<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1438 1438-30811 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46I, I47V, I54A, V82A, L90M L33F, K43T, Q58E, L89V L10I, I13V, I15V, R41K, D60K, I62V, L63A, A71V  
>1438-30811| codons 4-99
TLWQRPIVTVKVGGQLKEALLDTGADDTIFEEMNLPGKWTPKIVGGIGGFAKVREYKQVA
IEICGHKVIGTVLVGPTPANIIGRNVMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, L74I, Y115F, M184V, T215F K219Q K101P, K103S   V60I, D123E, I135T, D177E, T200A, I202V, D218E  
>1438-30811| codons 38-247
CTELEKEGKISKIGPENPYNTPIFAIKKKNSTRWRKIVDFRELNKRTQDFWEVQLGIPHP
AGLPKSKSVTVLDVGDAFFSVPLDKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPEIVIYQYVDDLYVGSDLEIGQHRAKVEELRQHLLRWGFFTP
EQKHQKEPPFLWMGYELHPDKWTVQPIVLP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006