Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2078 | 2078-30612 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | E138A, S162C, I178M, D192H, G196E, Q207E, F214L |
| >2078-30612| codons 38-246 CTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFRKQNPDMVIYQYVDDLYVGSHLEIEQHRTKIEELREHLLRWGLTTP DKKHQKEPPFLWMGYELHPDKWTVQPIVL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | N88D | I13V, K14R, L19I, K20T, R41K, K45KR, I64V, A71V, V77I |
| >2078-30612| codons 4-99 TLWQRPLVTVRIGGQITEALLDTGADNTVLEEMNLPGKWKPRMIGGIGGFIKVRQYDQIL VEICGHKVIGTVLIGPTPVNIIGRDLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |