Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1883 | 1883-30604 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74V | K219N | L100I, K103N | T39A, R83K, K122E, S162C, K173R, Q174R, G196E, Q207H, R211Q, F214FL, L228LH |
| >1883-30604| codons 38-247 CAEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKKTQDFWEVQLGIPHP AGIKKNKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFRRRNPDIVIYQYMDDLYVGSDLEIEQHRTKIEELRHHLLQWGLTTP DNKHQKEPPFHWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I50V, I54V, V82A | L33LF | L10I, I13IV, K20R, M36I, N37D, L63P, I64IV, K70R, A71V, Q92QK |
| >1883-30604| codons 4-99 TLWQRPIVTVKIGGQLREALLDTGADDTVFEEIDLPGRWKPKIIGGVGGFVKVRQYDQIP VEICGHRVIGTVLVGPTPANIIGRNLLTKIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |