Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1882 | 1882-30528 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, I84V, L90M | L10F, G73S | I13V, G16A, K20I, M36I, L63P, A71V |
| >1882-30528| codons 4-99 TLWQRPFVTVKIAGQLIEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFVKVRQYDQIP IEICGHKVISTVLVGPTPVNVIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y115YF, Q151M | K70KN, F77FL, F116Y | V118I, K122E, D123N, I135V, K173N, Q174R, D177E, G196E, T200TI, R211K, F214L | N137S |
| >1882-30528| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKDSTNWRKLVDLRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAFYSIPLDENFRKYTAFTIPSVNSETPGIRYQYNVLPMGWKGSP AIFQSSMTKILEPFRNRNPEIVIYQYMDDLYVGSDLEIEQHRIKIEELRQHLLKWGLTTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |