Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1714 | 1714-30529 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, M184V, L210W, T215Y | Y188L | E44D, V106L, V118I, K122E, G196E, R211K, E224D |
| >1714-30529| codons 38-247 CTELEKDGKISKIGPENPYNTPVFAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSLTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYVDDLLVGSDLEIEQHRTKIEELRQHLWKWGFYTP DKKHQKDPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V, L90M | L33F, N88ND | L10I, I13V, K20KR, E35D, M36I, N37D, I62V, L63P, I66V, A71T, I72K, V82I, I93L, C95F |
| >1714-30529| codons 4-99 TLWQRPIVTVKIGGQLREALLDTGADDTVFEDIDLPGRWKPKIIGGIGGFVKVRQYDQVP IEVCGHKTKGTVLVGPTPINVIGRDLMTQLGFTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |